![]() ![]() This information relates to an herbal, vitamin, mineral or other dietary supplement. Antimicrobial and cytotoxic agents from Calophyllum inophyllum. Yimdjo MC, Azebaze AG, Nkengfack AE, Meyer AM, Bodo B, Fomum ZT. Review of the scientific literature reveals mostly animal studies evaluating the efficacy of tamanu oil. The anti-HIV activity of the following coumarins has also been reviewed and includes: calophyllolide, inophyllum P (Soullatrolide), inophyllum B, inophyllum C, and inophyllum E. Ten 4-phenylcoumarins have also been isolated from the plant. Ali 1999įour pyranocoumarin derivatives have been isolated from the seeds of the plant, designated as inocalophyllins A (1), B (2), and their methyl esters (3, 4). Two epimers, inophynone and isoinophynone, were isolated from the leaves of the plant, as well as friedelin, canophyllol, and canophyllic acid. Caloxanthone E was isolated from the root heartwood of the plant. The root bark contains the xanthones caloxanthone A, B, C, and D. Two isomeric benzodipyranone derivatives have been isolated from the leaves. Several triterpenes, flavonoid glycosides, neoflavonoids, pyranoamentoflavone, and other bioactive compounds have been isolated from the plant. Xanthones isolated from the plant have antibacterial activity, and 4-phenyl coumarins obtained from its leaves may have antitumor-promoting activity. The oil is used in Chinese traditional medicine to treat rheumatism, skin infections, wounds, leprous nephritis, pain, eye diseases, and inflammation. The oil is valued for its analgesic and pain-relieving properties and has been used to treat neuralgia, rheumatism, and sciatica. The oil has also been topically applied to the neck area to treat sore throat. In Pacific island folk medicine, the oil has been topically applied to treat various ailments such as cuts, scrapes, burns, insect bites and stings, abrasions, acne and acne scars, psoriasis, diabetic sores, anal fissures, sunburn, dry or scaly skin, blisters, eczema, herpes sores, and to reduce foot and body odor. The oils of the seed and root have been used to treat wounds and scabies. All parts of the plant (bark, leaves, seeds) have been used medicinally as antiseptics, astringents, expectorants, diuretics, and purgatives. Tamanu has been used traditionally as a local medicine, and is sometimes considered to be the African, Asian, Polynesian, and Pacific Rim panacea. The mature green fruit is inedible and is about the size of an apricot. The plant has dark green oval leaves and white flowers with a yellow center. ![]() The trunk is typically thick and the bark is dark to grayish brown. It is a tropical evergreen plant that can grow up to 30 m in height. inophyllum is indigenous to Southeast Asia, and is also found in Southern India, Sri Lanka, and throughout the islands of Melanesia and Polynesia. The genus Calophyllum consists of approximately 130 species. Review of the scientific literature reveals little to no toxicity data on the plant. Tamanu oil may cause hypersensitivity reactions in patients with an existing allergy to plants in the Clusiaceae family. There is a case report in scientific literature of allergic contact dermatitis from tamanu oil. Information regarding safety and efficacy in pregnancy and lactation is lacking. None suggested because of lack of clinical data. The oil possesses antimicrobial and antiviral activity. ![]() All parts of the plant (ie, bark, leaves, seeds) have been used medically as antiseptics, astringents, expectorants, diuretics, and purgatives. Tamanu oil has been used traditionally as a local medicine, and is sometimes considered the African, Asian, Polynesian, and Pacific Rim panacea. Scientific Name(s): Calophyllum inophyllum L., Calophyllum tacamahacaĬommon Name(s): Alexandrian laurel, Dilo, Dolno, Fetau, Kamani, Kamanu, Tamanu, Tamanu oil, Ti ![]()
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